Catalogue

Background
The p21waf1 tumor suppressor protein shows no cross reactivity with the closely related inhibitors .p21waf1 is a specific inhibitor of cdkÕs, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including colon and breast carcinoma

Synonyms: p21waf1; hp21; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6

Source
Mice were immunized with a recombinant full length p21 protein.

Product
Provided as solution in phosphate buffered saline with 0.08% sodium azide

Product Form: Unconjugated

Purification Method: Protein A/G Chromatography

Concentration: See vial for concentration

Applications
1-5 ug /ml for Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)

Functional Analysis: Western Blotting

Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References
1) R. Erber, et.al. (1997) Pred. Oncol. 74, 383-389 2. Shen, J., et al. ‘Identification and Validation of Differences in Protein Levels in Normal, Premalignant, and Malignant Lung Cells and Tissues Using High-Throughput Western Array and Immunohistochemistry.’ Cancer Res., 66, 11194-11206 (2006).

Protein Reference(s)

Database Name: UniProt

Accession Number: P38936 (Human)

Species Accession: Human

Safety Datasheet(s) for this product: