Exalpha Biologicals, Inc.

Upcoming Meetings

7th International Ceramide Conference

Oct. 20-24, 2013

Montauk, Long Island, New York

Learn More

13th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases

November 3 - 6, 2013

San Juan, Puerto Rico

Learn More

Latest References

Luo Z, Luo P, Yu Y, Zhao Q, Zhao X, Cheng L. "SPARC promotes the development of erythroid progenitors." Exp Hematol. 2012 Jun 9

Learn More

Basu, G., et al. "Frequency distribution of SPARC in triple-negative breast cancer patients." J. Clin. Oncol., 29, 2011 (suppl 27; abstr 37)

Learn More

References

X1010 14-3-3 theta/tau
1. Kakinuma, N., et al. ?Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K?Akt signaling.? J. Cell Biol. 2008, 181, 537-549

2. Patel, A., et al. ?Host protein interactions with enteropathogenic Escherichia coli (EPEC): 14-3-3 binds Tir and has a role in EPEC-induced actin polymerization.? Cellular Microbiology, 2006, 8, 55-71
U115P ADAR2 (Adenosine Deaminase Acting on RNA 2)
1. Hideyama, T., et al. ?Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons? PLoS One, 7, e43469, 2012
T110M Alx-4
1. Rendl, Michael et al., 'Molecular Dissection of Mesenchymal-Epithelial Interactions in the Hair Follicle' Public Library of Science 2005, 3, 11, e331
A100M bax
1. Annis, M., et al, 'Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis' EMBO Journal 2005, 24, , 2096-2103
2. Soucie, E.L., et al, 'Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria' Molecular and Cell Biology 2001, 21, , 4725-4736
A205P BrdU (bromodeoxyuridine)
1. Robert K Dempsey, et al., 'Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenoug IGF-1 and GDNF' Journal of Neurochemistry 2003, 87, , 586-597
X1327K1 BrdU Cell Proliferation
1. Chang, V., et al, 'Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines.' Cancer Gene Therapy 2007, 14, , 927-933
2. Sekine, C., et al, 'Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors' Journal of Immunology 2008, 180, , 1954-1961
3. Matta, H., et al, 'Activation of alternative NF- B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 -converting enzyme inhibitory protein (vFLIP)' PNAS 2004, 101, , 9399-9404
X1545K BrdU IHC Kit
1. Sato, S., et al, 'Central control of bone remodeling by neuromedin U' Nature Medicine 2007, 13, , 1234-1240
X1114P Caspase-12 (IN)
1. Hetz, C., et al, 'Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein' EMBO Journal 2003, 22, , 5435-54
2. Hetz, C., et al, 'The Disulfide Isomerase Grp58 Is a Protective Factor against Prion Neurotoxicity' Journal of Neuroscience 2005, 25, , 2793-2802
3. Rao, Rammohan V., et al, 'Coupling Endoplasmic Reticulum Stress to the Cell Death Program' The Journal of Biological Chemistry 2002, 277, 24, 21836-21842
X1115P Caspase-12 (NT) (involved in Alzheimers)
1. Hetz, C., et al, 'Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein' EMBO Journal 2003, 22, , 5435-54
2. Hetz, C., et al, 'The Disulfide Isomerase Grp58 Is a Protective Factor against Prion Neurotoxicity' Journal of Neuroscience 2005, 25, , 2793-2802
3. Rao, Rammohan V., et al, 'Coupling Endoplasmic Reticulum Stress to the Cell Death Program' The Journal of Biological Chemistry 2002, 277, 24, 21836-21842
0141 CD14
1. Cappelli, G., et al, 'Human Macrophage Gamma Interferon Decreases Gene Expression but Not Replication of Mycobacterium tuberculosis: Analysis of the Host-Pathogen Reciprocal Influence on Transcription in a Comparison of Strains H37Rv and CMT97' Infectious Immunology 2001, 69, , 7262-7270
0144 CD14 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996
0162 CD16 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321
0164 CD16 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996
0194 CD19 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996
0032 CD3 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321
0034 CD3 PE
1. Takebayashi, M., et al, 'Blood dendritic cells are decreased in acute graft-versus-host disease' Bone Marrow Transplantation 2004, 33, , 989-996
AP04 CD4 APC
1. Chakrabarti, L.A., et al, 'Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection' Journal of Virology 2000, 74, , 1209-1223
0042 CD4 FITC
1. Tajima, Kenichirou et al, 'Immunomodulatory effects of cyclosporin A on human perioheral blood dendritic cell subsets' Immunology 2003, 108, 3, 321
0044 CD4 PE
1. O'Neill, E., et al, 'Dynamic Evolution of the Human Immunodeficiency Virus Type 1 Pathogenic Factor, Nef' Journal of Virology 2006, 80, 3, 1311-1320
2. Foster, J.L., et al, 'Genetic and Functional Diversity of Human Immunodeficiency Virus Type 1 Subtype B Nef Primary Isolates' Journal of Virology 2001, 75, , 1672-1680
3. Goldstein, S., et al, 'Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates' Journal of Virology 2005, 79, , 5153-5162
4. Chakrabarti, L.A., et al, 'A Truncated Form of Nef Selected during Pathogenic Reversion of Simian Immunodeficiency Virus SIVmac239{Delta}nef Increases Viral Replication' Journal of Virology 2003, 77, , 1234-1256
5. Chakrabarti, L.A., et al, 'Properties of the Surface Envelope Glycoprotein Associated with Virulence of Simian-Human Immunodeficiency Virus SHIVSF33A Molecular Clones' Journal of Virology 2002, 76, , 1588-1599
6. Luo, T., et al., 'Human Immunodeficiency Virus Type 1 Nef-Induced CD4 Cell Surface Downregulation Is Inhibited by Ikarugamycin' Journal of Virology 2001, 75, , 2488-2492
7. Anderson, S.J., et al, 'The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef' Journal of Virology 1994, 68, , 3092-3101
42A4 CD42a PE
1. Heilmann, C., et al, 'Staphylococcus aureus Fibronectin-Binding Protein (FnBP)?Mediated Adherence to Platelets, and Aggregation of Platelets Induced by FnBPA but Not by FnBPB' Journal of Infectious Disease 2004, 190, , 321-329
0541 CD54
1. Masakazu Nagafuku, et al, 'Reduction of Glycosphingolipid Levels in Lipid Rafts Affects the Expression State and Function of Glycosylphosphatidylinositol-anchored Proteins but Does Not Impair Signal Transduction via the T Cell Receptor' Journal of Biological Chemistry 2003, 278, 51, 51920-51927
0544 CD54 PE
1. Arpinati, M., et al, 'Use of anti-BDCA-2 antibody for detection of dendritic cells type-2 (DC2) in allogeneic hematopoietic stem cell transplantation' Bone Marrow Transplantation 2002, 29, , 887-891
0561 CD56
1. Horikawa, M., et al, 'Abnormal Natural Killer Cell Function in Systemic Sclerosis: Altered Cytokine Production and Defective Killing Activity' Journal of Investigative Dermatology 2005, 125, , 731-737
2. Ishimoto, H., et al, 'Midkine, a heparin-binding growth factor, selectively stimulates proliferation of definitive zone cells of the human fetal adrenal gland' Journal of Endocrinol. Metab 2006, 91, , 4050-4056
3. Muench, M., et al, 'Isolation of Definitive Zone and Chromaffin Cells Based upon Expression of CD56 (Neural Cell Adhesion Molecule) in the Human Fetal Adrenal Gland' Journal of Clinical Endocrinol. Metab 2003, 88, , 3921-3930
4. Miles, L.A., et al, 'Cell-Surface Actin Binds Plasminogen and Modulates Neurotransmitter Release from Catecholaminergic Cells' Journal of Neuroscience 2006, 26, , 13017-13024
0081 CD8
1. Kawabata, S., et al, 'Induction of Th2 Cytokine Expression for p27-Specific IgA B Cell Responses after Targeted Lymph Node Immunization with Simian Immunodeficiency Virus Antigens in Rhesus Macaques' Journal of Infectious Disease 1998, 177, , 26-33
AP08 CD8 APC
1. Chakrabarti, L.A., et al, 'Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection' Journal of Virology 2000, 74, , 1209-1223
0084 CD8 PE
1. Sauermann, U., et al, 'Homozygosity for a Conserved Mhc Class II DQ-DRB Haplotype Is Associated with Rapid Disease Progression in Simian Immunodeficiency Virus?Infected Macaques: Results from a Prospective Study' Journal of Infectious Disease 2000, 182, , 716-724
X1700P Ceramide Glycosyltransferase
1. D'Angelo, G., et a, 'Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide.' Nature 2007, 449, , 62-67
X1179P chx 10 (CT)
1. Qiu, F., et al, 'A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors' Journal of Neuroscience 2008, 28, , 3392-3403
2. Elshatory, Y., et a, 'Islet-1 Controls the Differentiation of Retinal Bipolar and Cholinergic Amacrine Cells' Journal of Neuroscience 2007, 27, , 12707-12720
3. Osakada, F., et al, 'Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals' Journal of Neuroscience 2007, 27, , 4210-4219
4. Nittner, D., et al. 'Synthetic lethality between Rb, p53 and Dicer or miR-17?92 in retinal progenitors suppresses retinoblastoma formation.' Nature Cell Biology (2012), 14, 958?965
X1180P chx 10 (NT)
1. Qiu, F., et al, 'A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors' Journal of Neuroscience 2008, 28, , 3392-3403
2. Elshatory, Y., et a, 'Islet-1 Controls the Differentiation of Retinal Bipolar and Cholinergic Amacrine Cells' Journal of Neuroscience 2007, 27, , 12707-12720
3. Osakada, F., et al, 'Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals' Journal of Neuroscience 2007, 27, , 4210-4219
4. Nittner, D., et al. 'Synthetic lethality between Rb, p53 and Dicer or miR-17?92 in retinal progenitors suppresses retinoblastoma formation.' Nature Cell Biology (2012), 14, 958?965
X1789P Collapsin response mediator protein 1 (CT)
1. Nilsen, J., et al, Estradiol In Vivo Regulation of Brain Mitochondrial Proteome, Journal of Neuroscience 2007, 27, , 14069-14077
X1790P Collapsin response mediator protein 1 (IN)
1. Nilsen, J., et al, Estradiol In Vivo Regulation of Brain Mitochondrial Proteome Journal of Neuroscience 2007, 27, , 14069-14077
A090M COX II (cyclooxygenase II)
1. Kaneshiro, Y., et al, 'Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats' Kidney International 2006, 70, , 641-646
X1588P DAP12
1. Zou, W., et al, 'DAP12 Couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk' Molecultar Cell 2008, 31, 3, 422-431
F115P EBNA 3A
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Dalbi
F120P EBNA 3B
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Gordadze, A.V., et al, 'Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus' Journal of Virology 2001, 75, , 5899-5912
F125P EBNA 3C
1. Anderton, E., et al, 'Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma' Oncogene 2007, 27, , 421-433
2. O'Nions, J., et al, 'Epstein?Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2' Oncogene 2003, 22, , 7181-7191
3. Jiménez-Ramírez, C., et al, 'Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter' Journal of Virology 2006, 80, , 11200-11208
4. Yuan, J., et al, 'Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication' Journal of Virology 2006, 80, , 2548-2565
5. Hong, G.K., et al, 'Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model' Journal of Virology 2005, 79, , 13993-14003
6. Rosendorff, A., et al, 'EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain' Journal of Virology 2004, 78, , 367-377
7. Maruo, S., et al, 'Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth' Journal of Virology 2003, 77, , 10437-10447
8. Gordadze, A.V., et al, 'Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus' Journal of Virology 2001, 75, , 5899-5912
X1165P Farnesyl
1. Clase, A.C., et al, 'The Pseudorabies Virus Us2 Protein, a Virion Tegument Component, Is Prenylated in Infected Cells' Journal of Virology 2003, 77, , 12285-12298
0DR2 HLA-DR FITC
1. Weidmann, A., et al, 'Proteolytic Cleavage of the Fusion Protein but Not Membrane Fusion Is Required for Measles Virus-Induced Immunosuppression In Vitro' Journal of Virology 2000, 74, , 1985-1993
0G14 IgG1 PE
1. Luo, T., et al., 'Human Immunodeficiency Virus Type 1 Nef-Induced CD4 Cell Surface Downregulation Is Inhibited by Ikarugamycin' Journal of Virology 2001, 75, , 2488-2492
F105P KSHV/HHV8 (cyclin)
1. Jarviluoma, Annika et al, 'KSHV viral cyclin binds to p27KIP1 in primary effusion lymphomas' Blood 2004, 104, 10, 3349-3354
F100P KSHV/HHV8 (mal 62/ORF 62)
1. Watanabe, T., et al, 'Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Prolongs the Life Span of Primary Human Umbilical Vein Endothelial Cells' Journal of Virology 2003, 77, , 6188-6196
T105P LEF-1
1. Labbe, Etienne, et al., 'Association of Smads with lymphoid enhancer binding factor 1/T cell specific factor mediates coopertive signaling by the transforming growth factor-Beta and Wnt pathways' Proceedings of the National Acadamy of Science 2000, 97, 15, 8358-8363
X1076M LEF-1 all isoforms
1. Aoki, M., et al, 'Oncogenic transformation by -catenin: deletion analysis and characterization of selected target genes' Oncogene 2002, 21, , 6983=8991
T100M LEF-1beta catenin
1. Driskell. Ryan R., et al, 'Wnt-responsive element controls Lef-1 promotor expressions durig submucosal galnd morphogenesis' American Journal of Physiology Lung Cell Moleculatr Physiology 2004, 287, , 752-763
2. Li. Feng-Qian, et al., 'Lymphoid Enhancer Factor-1 Links Two Hereditary Leukemia Syndromes through Core-binding Factor-alpha Regulation of ELA2' Journal of Biological Chemistry 2004, 279, 4, 2873-2884
3. Kahler, Rachel A., et al., 'Lymphoid Enhancer Factor-1 and Beta Catenin Inhibit Runx2-dependent Transcriptional Activation of the Osteocalcin Promotor' Journal of Biological Chemicstry 2003, 278, 14, 11937-11944
4. Grueneberg, D.A., et al., 'A Functional Screen in Human Cells Identifies UBF2 as an RNA Polymerase II Transcription Factor That Enhances the
T105M LEF/TCF/HMG
1. Holnthoner, Wolfgang, et al., 'Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Trnscription in Human Endothelial Cells' Journal of Biological Chemistry 2002, 277, 48, 45847-45853
2. Willinger, T., et al, 'Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo' Journal of Immunology 2006, 176, , 1439-
X1647P Lipid Phosphate Phosphatase Related Protein 2
1. Zhao, Yutong, et al, 'Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF- B activation and interleukin-8 secretion in human bronchial epithelial cells' Biochem Journal 2005, 385, , 493-502
X1648P Lipid Phosphate Phosphatase Related Protein 3
1. Zhao, Yutong, et al, 'Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF- B activation and interleukin-8 secretion in human bronchial epithelial cells' Biochem Journal 2005, 385, , 493-502
X1570P Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT
1. Yun, C. Chris, et al, 'LPA2 receptor mediates mitogenic signals in human colon cancer cells' American Journal of Cell Physiolgy 2005, 289, , C2-C11
2. Shida, D., et a, 'Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer' Laboratory Investigation 2004, 84, , 1352-1362
c174p Lysophosphatidic Acid Receptor 1 CT (EDG-2)
1. Hu, Xiaojie, et al, 'Lysophosphatidic acid (LPA) protects primary chronic lymphocytic leukemia (CLL) cells from apoptosis through LPA receptor activation of the anti-apoptotic protein AKT/PKB' Journal of Biological Chemistry 2005, 280, , 9498-9508
2. Shida, Dai, et al, 'Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer' Laboratory Investigation 2004, 84, , 1352-1362
3. Shida, Dai et al, 'Lysophosphatidic Acid (LPA) Enhances the Metastatic Potential of Human Colon Carcinoma DLD1 Cells through LPA1' Cancer Research 2003, 63, , 1706-1711
Z115M M13 bacteriophage (gp3)
1. Sakai, Keiko et al, 'Isolation and Characterization of Phage-Displayed Single Chain Antibodies Recognizing Nonreducing Terminal Mannose Residues. 1. A New Strategy for Generation of Anti-Carbohydrate Antibodies' Biochemistry 2007, 46, 1, 253-262
2. Qi,Cai et al, 'Phage M13KO7 detection with biosensor based on imaging ellipsometry and AFM microscopic confirmation' Virus Research 2009, 140, , 79-84
3. Tragoolpua, Khajornsak et al, 'Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells' BMC Biotechnology 2008, 8, 5, Online only

Page 1 of 2 1 2 Next Page