Mip1a
- Product Code: X1244C
- Size: 20 µg
- Availability:
In Stock - Price (USD): $375
Cat #
Data Sheet
Product Name
Mip1a
Synonyms
Macrophage Inflammatory Protein 1 ; CCL3
Product Type
Synthetic Protein
Applications
Activity Assay
Size
20 µg
Price (USD)
$375
Background
MIP-1 (Macrophage Inflammatory Protein 1 or CCL3) is a monocyte chemoattractant which has chemoattractant and adhesive effects on lymphocytes, preferentially attracting CD8+ cells. MIP-1 has also been shown to attract B cells and also eosinophils. It has also been identified as a stem cell inhibitory factor which can inhibit the proliferation of hematopoietic stem cells in vitro and in vivo. Receptors for MIP-1 are CCR1 and CCR5.
Formulation
Lyophilized
Customer Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
References
1. Menten, P. et al. 'Macrophage inflammatory protein-1.' Cytokine Growth Factor Rev. 2002: 13, 455-4812. Owen-Lynch, P.J., et al. 'The growth inhibitory role and potential clinical value of macrophage inflammatory protein 1 alpha in myeloid leukaemias.' Leuk. Lymphoma 1998: 30, 41-53
3. Broxmeyer, H.E., et al. 'Advances in undestanding of biological effects of interleukin-11, leukemia inhibitory factor, and macrophage inflammatory protein 1 alpha.' Curr. Opin. Hematol. 1994: 1, 197-202.