CD42a PE
- Product Code: 42A4
- Size: 100 Tests
- Availability:
In Stock - Price (USD): $185
Cat #
Data Sheet
Product Name
CD42a PE
Synonyms
CD42a PE
Host/Source
Mouse
Clone
ESS
Isotype
IgG1
Product Type
Single-Color Reagent
Reactivity
Human
Applications
Flow Cytometry
Purification
Protein A/G Chromatography
Size
100 Tests
Price (USD)
$185
Background
Single-chain membrane glycoprotein that forms a non-covalent complex with GPIb. (MW23kDa) Reactivity with resting and activated platelets, weakly on monocytes, megakaryocytes and attachment site for the platelet plasma membrane to the submembrane cytoskeleton. GPIb/IX complex, functions as the receptor for ristocetin-induced binding of von Willebrand factor and as the von Willebrand factor-depend adhesion receptor.
Formulation
Provided as sterile filtered solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein
Customer Storage
Product should be stored at 4-8°C. DO NOT FREEZE
Database Links:
| SwissProt | P14770 | Human |
Product Specific References
This product has been used in:
1. Heilmann, C., et al, 'Staphylococcus aureus Fibronectin-Binding Protein (FnBP)?Mediated Adherence to Platelets, and Aggregation of Platelets Induced by FnBPA but Not by FnBPB' Journal of Infectious Disease 2004, 190, , 321-329References
1. Detection of platelet activation with monoclonal antibodies and flow cytometry. Fijnheer R., Modderman P.W., Veldman H., et al. Transfusion 1990:30:20-252. Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane Du X, Beutler L., Ruan C., Castaldi P.A., and Berndt M.C., Blood 1987:69:1524-1527
3. Structure of the glycoprotein Ib-IX complex from platelet membranes Fox JEB, Aggerbeck L.P., Berndt M.C., J. Biol. Chem. 1988:263:4882-4890
4. Leucocyte Typing IV: White Cell Differentiation Antigens Nieuwenhuis H.K. Report on functional studies. In: Knapp W., Dorken B., Gilks W.R., et al, eds. Oxford: Oxford University Press: 1989:1002-1003.