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Lass1 (Cross reacts with GDF1) Blocking Peptide Catalog Number: X2294B Prouct Type: Blocking Peptide Product Size/Price (US$): 50 µg, $110 Species Reactivity: Human Applications: Western Blot Immunogen: Synthetic peptide derived from the human Lass1 protein. Usage: For use with Lass1 polyclonal antibodies (Cat. No. X2084P & X2310P). Description: LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane; LAss1 is a multi-pass membrane protein. Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Storage Conditions: Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles Database Links: SwissProt P27544 Human Click link here to download datasheet .pdf file |
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